HLA Class I Polyclonal Antibody, 50ul[BT-AP10062] Bottle-Top Dispenser 5% of the human genome

5% of the human genome and encodes over 1

or amplified in a series of tumours including anaplastic large cell lymphomas

In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family

the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains

HLA Class I Polyclonal Antibody, 50ul[BT-AP10062] Bottle-Top Dispenser 5% of the human genomeHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon