STEAP2 Polyclonal Antibody, 100ul Glassware Sets Inhibition of the encoded protein

Inhibition of the encoded protein restores hemostasis in animal models of hemophilia

Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase| H+ transporting| mitochondrial Fo complex| subunit F2) and this gene

the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections

Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK)

RAD17 checkpoint clamp loader component encoded by RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17

STEAP2 Polyclonal Antibody, 100ul Glassware Sets Inhibition of the encoded proteinSTEAP2 is a member of the STEAP family and encodes a multi pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression.