Paxillin Polyclonal Antibody, 100ul[BT-AP06956] Cell Labeling & Imaging encoding nearly 900 genes

encoding nearly 900 genes

Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation

The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen

Crohn's disease and inflammatory bowel disease

Paxillin Polyclonal Antibody, 100ul[BT-AP06956] Cell Labeling & Imaging encoding nearly 900 genesPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.