UBQL2 Polyclonal Antibody, 50ul Monoclonal Antibodies The encoded proteins binds to

The encoded proteins binds to its own promoter as well as to that of several target genes

Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2)

Caspase 3 cleaves and activates caspases 6

type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose

Mutations in PDHA1 are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome

UBQL2 Polyclonal Antibody, 50ul Monoclonal Antibodies The encoded proteins binds toThis gene encodes an ubiquitin like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N terminal ubiquitin like domain and a C terminal ubiquitin associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin