mGluR-8 Polyclonal Antibody, 100ul Cell Proliferation Mutations in this gene are

Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP)

a cytosolic phosphoprotein implicated in tumorigenesis

and thus mediates the anti-apoptotic signals from TNF receptors

This gene is classified as a pseudogene because a splice donor in the 3' UTR has changed compared to other family members| rendering the transcript a candidate for nonsense-mediated mRNA decay (NMD)

TMPRSS3 encodes transmembrane protease serine 3 that belongs to the serine protease family

mGluR-8 Polyclonal Antibody, 100ul Cell Proliferation Mutations in this gene areL glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative