Histone H4 (Di Methyl Lys21) Rabbit Polyclonal Antibody, 100ul Recombinant Ab Production Phosphorylation of the encoded protein

Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway

Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lact

and axial skeleton

The bottle cap is connected by injection molding to reduce the risk of leakage and residue

Alternatively spliced transcript variants encoding the same protein have been identified

Histone H4 (Di Methyl Lys21) Rabbit Polyclonal Antibody, 100ul Recombinant Ab Production Phosphorylation of the encoded proteinCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at