AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis The protein encoded by this

The protein encoded by this gene is involved in processes including neurite growth and migration

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis

The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide

The primary sequences of the three human mitochondria

Tyrosine phosphorylation seems to occur only at the plasma membrane

AIRE-1 Polyclonal Antibody, 50ul[BT-AP00311] DNA Synthesis The protein encoded by thisAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and