PC-PLD1(Phospho Ser561) Polyclonal Antibody, 20ul Immunoassays 48 (DFNB48)

48 (DFNB48)

Alterations in this region have been associated with the Beckwith-Wiedemann syndrome

Contains 1 chromo domain

SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha and CAB39

The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration

PC-PLD1(Phospho Ser561) Polyclonal Antibody, 20ul Immunoassays 48 (DFNB48)This gene encodes a phosphatidylcholine specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.