Apaf-1 Polyclonal Antibody, 100ul Drug Development and Evaluation ELOVL3 (ELOVL fatty acid elongase

ELOVL3 (ELOVL fatty acid elongase 3) encodes a protein that belongs to the GNS1/SUR4 family

The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death

The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin

There is a high degree of homology between aldolase A and C

The protein encoded by this gene is a member of the folate receptor (FOLR) family

Apaf-1 Polyclonal Antibody, 100ul Drug Development and Evaluation ELOVL3 (ELOVL fatty acid elongaseAPAF1 encodes a cytoplasmic protein that initiates apoptosis. Apoptotic protease activating factor 1 contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade