UPAR Rabbit Polyclonal Antibody, 20ul Live Cell Imaging Contains 1 IRS-type PTB domain

Contains 1 IRS-type PTB domain

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system

Some members of this family bind to DNA by zinc-mediated secondary structures called zinc fingers| and are involved in transcriptional regulation

The encoded protein has been shown to interact with the cancer developmental regulators SMAD2

Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory

UPAR Rabbit Polyclonal Antibody, 20ul Live Cell Imaging Contains 1 IRS-type PTB domainActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.