SRRM1 Polyclonal Antibody, 20ul Funnels Biosealing: Yes

Biosealing: Yes

Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome

Belongs to the FAM3 family

Its expression is up-regulated by estrogens and progestins

The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities

SRRM1 Polyclonal Antibody, 20ul Funnels Biosealing: YesPart of pre and post splicing multiprotein mRNP complexes. Involved in numerous pre mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE) dependent splicing activation by bridging together sequence specific (SR family proteins, SFRS4, SFRS5 and TRA2B SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3' end cleavage independently of the formation of an exon junction complex. Binds both