Mouse C-C Chemokine Receptor Type 2, CCR2 ELISA Kit , 96T Monoclonal Antibodies Plays a critical role in

Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls

The 9-1-1 complex associates with LIG1| POLB| FEN1| RAD17| HDAC1| RPA1 and RPA2

the LDL receptor-related proteins LRP1

Additional isoforms produced by alternative splicing seem to exist

This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity

Mouse C-C Chemokine Receptor Type 2, CCR2 ELISA Kit , 96T Monoclonal Antibodies Plays a critical role inKey functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines (PubMed: 8631787, PubMed: 8662823, PubMed: 8996246). Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity). Also acts as a receptor for the beta defensin DEFB106A DEFB106B (By similarity). Regulates the expression of T cell