NOXA1 Polyclonal Antibody, 100ul Cell Screening and Imaging and the structural diversity in

and the structural diversity in the gene products arises from alternative mRNA splicing

It encodes a type 1 membrane bound protease that is expressed in many tissues

The protein is localized to the outer limiting membrane in the retina| and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions

The encoded protein cleaves amyloid precursor protein into amyloid beta peptide

and interleukin 1 receptor

NOXA1 Polyclonal Antibody, 100ul Cell Screening and Imaging and the structural diversity inThis gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N terminal tetratricopeptide domains and a C terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene.