SorLA Monoclonal Antibody, 100ul[BT-MCA1151] Monoclonal Antibody Preparation The encoded protein is a

The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes

Very weak expression in small intestine

Negative regulator of host innate immune defense against viruses

Several pseudogenes have been identified

Multiple pseudogenes on chromosome 9

SorLA Monoclonal Antibody, 100ul[BT-MCA1151] Monoclonal Antibody Preparation The encoded protein is aThis gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting.