ASPP2 Polyclonal Antibody, 100ul Funnels which is required for TNF-alpha-mediated

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

Mutations in this gene are associated with lung cancer

This gene encodes multiple isoforms that may undergo similar proteolytic processing

The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10

The protein encoded by this gene is cell-cycle regulated| and has nuclear localization

ASPP2 Polyclonal Antibody, 100ul Funnels which is required for TNF-alpha-mediatedThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different