Histone H2B(Phospho Ser32) Polyclonal Antibody, 50ul Microplate Mixer Belongs to the MMP37 family

Belongs to the MMP37 family

and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis

binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium

Multiple alternatively spliced variants have been found in normal and cancerous tissues

releasing the kinase domain to allow N-terminus-mediated dimerization and kinase activation by transautophosphorylation

Histone H2B(Phospho Ser32) Polyclonal Antibody, 50ul Microplate Mixer Belongs to the MMP37 familyHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.