Collagen XVIII alpha 1(Cleaved-His1572) Rabbit Polyclonal Antibody, 100ul Site-directed Mutagenesis The protein encoded by this

The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region

The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites| implicating a role in determining and stabilizing dentritic shape during neuron development

Several transcript variants encoding different isoforms have been found for MARK3

an arrangement which is thought to have evolved by a series of gene duplications

The SH2 (Src Homology 2) domain is a structurally conserved motif that contains two alpha helices and seven beta strands and is found in a variety of proteins that are involved in signal transduction throughout the cell

Collagen XVIII alpha 1(Cleaved-His1572) Rabbit Polyclonal Antibody, 100ul Site-directed Mutagenesis The protein encoded by thisThis gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins extracellular matrix proteins that contain multiple triple helix domains (collagenous domains) interrupted by non collagenous domains. A long isoform of the protein has an N terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C terminal domain results in