DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection Potassium-transporting ATPase alpha chain 2

Potassium-transporting ATPase alpha chain 2 encoded by ATP12A belongs to the family of P-type cation transport ATPases

Multiple pseudogenes of this gene have been identified

Inactivating variants of this gene result in the recessive Lutheran null phenotype

Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17

Cholesterol side-chain cleavage enzyme mitochondrial localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone

DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection Potassium-transporting ATPase alpha chain 2Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53