VPS72 Polyclonal Antibody, 100ul Contamination Detection & Removal Mutations in this gene are

Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A

elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain

subcellular location:Localizes in centromeres during late telophase and early G1

The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily

It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification

VPS72 Polyclonal Antibody, 100ul Contamination Detection & Removal Mutations in this gene areThe protein encoded by VPS72 (vacuolar protein sorting 72 homolog) is a shared subunit of two multi component complexes, the histone acetyltransferase complex TRRAP TIP60 as well as the chromatin remodeling SRCAP containing complex. The TRRAP TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP containing complex catalyzes the exchange of histone H2A with the