DEN1A Rabbit Polyclonal Antibody, 50ul Fluorescent Staining eosinophils and natural killer cells
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DEN1A Rabbit Polyclonal Antibody, 50ul Fluorescent Staining eosinophils and natural killer cellsClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010
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