IL23R Polyclonal Antibody, 20ul Pipette Controller The encoded protein plays a

The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

This gene shares its 5' exon with the overlapping gene

Mutations in this gene result in primary ciliary dyskinesia-24

Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma

Mutations in NME1 have been identified in aggressive neuroblastomas

IL23R Polyclonal Antibody, 20ul Pipette Controller The encoded protein plays aThe protein encoded by this gene is a subunit of the receptor for IL23A IL23. This protein pairs with the receptor molecule IL12RB1 IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand dependent manner.