INPP5J Polyclonal Antibody, 100ul Protein Analysis Mutations in ACVR1B are associated

Mutations in ACVR1B are associated with pituitary tumors

This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators

|PTM:Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes

including autoimmune diseases

There is a pseudogene for this gene on chromosome 2

INPP5J Polyclonal Antibody, 100ul Protein Analysis Mutations in ACVR1B are associatedInositol 5 phosphatase, which converts inositol 1,4,5 trisphosphate to inositol 1,4 bisphosphate. Also converts phosphatidylinositol 4,5 bisphosphate to phosphatidylinositol 4 phosphate and inositol 1,3,4,5 tetrakisphosphate to inositol 1,3,4 trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate binding proteins that are present at membranes ruffles.