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Rb(Phospho Ser807) Polyclonal Antibody, 20ul Primary Antibodies although not all variants have

SKU: 55510002811

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Rb(Phospho Ser807) Polyclonal Antibody, 20ul Primary Antibodies although not all variants haveThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

although not all variants have had their full-length sequences determined

designated Q20*) which blocks expression of this protein

It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation

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Rb(Phospho Ser807) Polyclonal Antibody, 20ul Primary Antibodies although not all variants haveThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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