ACTR-IB Polyclonal Antibody, 100ul Diagnostic Probes & Oligos There have been conflicting reports

There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations

The encoded protein homodimerizes and functions as an outwardly rectifying channel

The protein encoded by this gene is a member of kinesin-like protein family

Component of the DREAM complex (also named LINC complex) at least composed of E2F4| E2F5| LIN9| LIN37| LIN52| LIN54| MYBL1| MYBL2| RBL1| RBL2| RBBP4| TFDP1 and TFDP2

The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases| suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery

ACTR-IB Polyclonal Antibody, 100ul Diagnostic Probes & Oligos There have been conflicting reportsACVR1B encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor beta (TGF beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in ACVR1B are