Raf-1(Phospho Thr269) Polyclonal Antibody, 20ul Contamination Detection & Removal The product of OTUB1 (OTU

The product of OTUB1 (OTU deubiquitinase

Cyclin D1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb

mature peptide and a C-terminal propeptide

Two transcript variants encoding the same protein but differing in the 5' UTR

and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage

Raf-1(Phospho Thr269) Polyclonal Antibody, 20ul Contamination Detection & Removal The product of OTUB1 (OTUThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.