Rat Pituitary Adenylate Cyclase-activating Polypeptide, ADCYAP1 ELISA Kit, 96T 3D Culture RAN-binding protein-16 is a member

RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors

chromosome segregation

enzyme regulation:Appears to be activated by multiple phosphorylations on threonine and serine residues

The proteins encoded by this gene are located at the outer mitochondrial membrane

Golgi-associated microtubules through recruitment of CLASP1 and CLASP2

Rat Pituitary Adenylate Cyclase-activating Polypeptide, ADCYAP1 ELISA Kit, 96T 3D Culture RAN-binding protein-16 is a memberBinding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells (By similarity). Promotes neuron projection development through the RAPGEF2 Rap1 B Raf ERK pathway. In chromaffin cells, induces long lasting increase of intracellular calcium concentrations and neuroendocrine secretion (PubMed: 18198219). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity).