RBM8A Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables ABC genes are divided into

ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| and White)

Highest expression in lung and skeletal muscle

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

Transcripts from this gene share exons with some transcripts from the C22orf29 gene

Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections

RBM8A Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables ABC genes are divided intoThis gene encodes a protein with a conserved RNA binding motif. The protein is found predominantly in the nucleus although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present thus coupling pre and post mRNA splicing