CD59 Polyclonal Antibody, 50ul[BT-AP01603] Protein Modification Homodimerization and interaction with phosphorylated

Homodimerization and interaction with phosphorylated CBL occurs via its C-terminal domain

Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle| proliferation| and developmental processes

They cycle between inactive GDP-bound and activated GTP-bound states

A transcript variant retaining intronic sequence and encoding a shorter isoform has been described

has a high affinity for Zinc

CD59 Polyclonal Antibody, 50ul[BT-AP01603] Protein Modification Homodimerization and interaction with phosphorylatedCDC7 (cell division cycle 7) encodes a cell division cycle protein with kinase activity that is critical for the G1 S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.