HECW1 Polyclonal Antibody, 20ul Serum LGALS3BP has been found elevated

LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV)

other organisms lack mariner transposase domain

It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand

suggesting that it may play a role in regulating genes in germ cells

It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta

HECW1 Polyclonal Antibody, 20ul Serum LGALS3BP has been found elevatedE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW