CRYL1 Rabbit Polyclonal Antibody, 100ul Sampling Tubes Several transcript variants have been

Several transcript variants have been found for this gene

Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function

Mutations in this gene cause Alexander disease

subcellular location:Colocalizes with endosomes

Widely expressed in myeloid leukemia cell lines

CRYL1 Rabbit Polyclonal Antibody, 100ul Sampling Tubes Several transcript variants have beenThe uronate cycle functions as an alternative glucose metabolic pathway accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L gulonate into dehydro L gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye.