SH2B3 Polyclonal Antibody, 20ul Recombinant Protein which is required for TNF-alpha-mediated

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

The protein is highly sensitive to external pH and this

Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini

Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome

or GRIN2D) and NR3 (GRIN3A or GRIN3B)

SH2B3 Polyclonal Antibody, 20ul Recombinant Protein which is required for TNF-alpha-mediatedThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced