GST-Tag Polyclonal Antibody, 100ul Buffer Solutions IRX3 is a member of

IRX3 is a member of the Iroquois homeobox gene family (see IRX1

Overexpression of this gene may play a role in leukemogenesis| and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

thereby forming the transcription factor complex AP-1

are found in a cluster on chromosome 1

GST-Tag Polyclonal Antibody, 100ul Buffer Solutions IRX3 is a member ofGST (Glutathione S Transferase) is a widely used protein tag encoded by the Schistosoma japonicum. GST provides both an easily detectable tag and a simple purification process with little effect on the biological function of the protein of interest. Antibodies to GST are useful for checking protein expression both in plaques and on Western blots as well as for immunoaffinity purification of proteins expressed in cells.