PDS5B Polyclonal Antibody, 100ul Buffers & Solutions the gene encoding VWA5A maps

the gene encoding VWA5A maps to human chromosome 11q24

RNA drug development

Mutations in this gene may be associated with Loeys-Dietz syndrome

Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin

and Brooke-Spiegler syndrome

PDS5B Polyclonal Antibody, 100ul Buffers & Solutions the gene encoding VWA5A mapsThis gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor suppressor gene.