CD6 Polyclonal Antibody, 50ul[BT-AP01912] Apoptosis & Autophagy A mutation in this gene

A mutation in this gene was associated with mental retardation

a multisystem developmental disorder

and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family

|polymorphism:Two forms exist

This protein cleaves and activates caspases 6

CD6 Polyclonal Antibody, 50ul[BT-AP01912] Apoptosis & Autophagy A mutation in this geneThe protein encoded by CTSL is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha 1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein (cathepsin L) has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular