CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays Does not have core 4

Does not have core 4 O-glycan or I-branching enzyme activity

Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction

A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family

suggesting that it may be involved in extracellular matrix adhesion

integrin alphaVbeta3

CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays Does not have core 4This gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis multiple familial trichoepithelioma and Brooke Spiegler syndrome. Alternate transcriptional splice variants encoding different isoforms have been characterized.