MCR Polyclonal Antibody, 50ul Contamination Detection & Removal STK3 (serine/threonine kinase 3) encodes

STK3 (serine/threonine kinase 3) encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor

and mutations in it have been associated with malignant rhabdoid tumors

Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease| and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease

CD33 (MIM 159590))

500 mL maximum RCF: 6

MCR Polyclonal Antibody, 50ul Contamination Detection & Removal STK3 (serine/threonine kinase 3) encodesThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are