DIRC2 Polyclonal Antibody, 100ul In vitro Assessment CALD1 encodes a calmodulin- and

CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction

This cyclin was found to bind to important cell cycle regulators

The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site| and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton| possibly by direct association with actin or spectrin

Reduced expression of this protein has been implicated in cardiomyopathies

Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

DIRC2 Polyclonal Antibody, 100ul In vitro Assessment CALD1 encodes a calmodulin- andThis gene encodes a membrane bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.