MaxiKBeta2 Polyclonal Antibody, 20ul Proteases Mutations in DOK7 are a

Mutations in DOK7 are a cause of familial limb-girdle myasthenia autosomal recessive

ATG16L2 may play a role in autophagy

The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family

voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability

It is a membrane protein and belongs to the protein family containing FAR-17a domain

MaxiKBeta2 Polyclonal Antibody, 20ul Proteases Mutations in DOK7 are aMaxiK channels are large conductance, voltage and calcium sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore forming alpha subunit and the modulatory beta subunit. Calcium activated potassium channel subunit beta 2 encoded by KCNMB2 is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents.