ALS2 Polyclonal Antibody, 20ul Serum & Sample Tubes The function of this protein

The function of this protein is unknown

Members of this family are important during development

Mutations in PHKA1 cause glycogen storage disease type 9D

The chromobox 3 encoded by CBX3 binds DNA and is a component of heterochromatin

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45

ALS2 Polyclonal Antibody, 20ul Serum & Sample Tubes The function of this proteinThe protein encoded by this gene contains an ATS1 RCC1 like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.