Phospho-20S Proteasome Alpha3 (S250) Polyclonal Antibody, 20ul Antibodies Alpha-2-macroglobulin is a protease inhibitor

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter

The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end

Some isoforms dominantly inhibit the activity of other estrogen receptor family members

The association with SMAD4 is important for the translocation of this protein into the nucleus

GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation

Phospho-20S Proteasome Alpha3 (S250) Polyclonal Antibody, 20ul Antibodies Alpha-2-macroglobulin is a protease inhibitorThe proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP ubiquitin dependent process in a non lysosomal pathway. An essential function