Porcine Angiopoietin 2, ANG-2 ELISA Kit, 96T Microplate Mixer Functions with TAF6L to activate

Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (PubMed: 31005419)

which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus

may also be involved

This enzyme is demonstrated to participate in the ubiquitination of p53

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins

Porcine Angiopoietin 2, ANG-2 ELISA Kit, 96T Microplate Mixer Functions with TAF6L to activateBinds to TEK TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2 mediated loosening of cell matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus