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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture The protein may be involved

SKU: 49318005994

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture The protein may be involvedBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

Store: gaabil.dk · Domain: gaabil.dk

Description

The protein may be involved in transduction of high-temperature heat responses in sensory ganglia

Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes

Inhibitors of the encoded protein may be effective in treating congestive heart failure

It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture The protein may be involvedBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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