CNOT2(Phospho Ser101) Polyclonal Antibody, 50ul Monoclonal Antibodies Required for collagen VII (COL7A1)

Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers

Multiple transcript variants encoding different isoforms have been found for PHF1

All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies

The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates

Transcript variants utilizing three different alternative non-coding first exons have been described

CNOT2(Phospho Ser101) Polyclonal Antibody, 50ul Monoclonal Antibodies Required for collagen VII (COL7A1)This gene encodes a subunit of the multi component CCR4 NOT complex. The CCR4 NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.