EFS Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation Two transcript variants encoding the

Two transcript variants encoding the same protein have been found for APOL2

such as cell division

play key roles in receptor-linked signaling pathways that control cell growth and differentiation

Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia

Alternative splicing of this gene results in multiple transcript variants encoding the same protein

EFS Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation Two transcript variants encoding theThe longest protein isoform encoded by this gene contains an SH3 domain which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene.