MOB1(Phospho-Thr12) Rabbit Polyclonal Antibody, 20ul Long RNA Synthesis leucine-rich motif of approximately 60

leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins

and is a member of a small gene family

Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway| thereby allowing activation and nuclear translocation of the NFKB complex

tissue specificity:Widely expressed

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division

MOB1(Phospho-Thr12) Rabbit Polyclonal Antibody, 20ul Long RNA Synthesis leucine-rich motif of approximately 60The protein encoded by this gene is a component of the Hippo signaling pathway which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.