SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Mammals have three related thioredoxin

Mammals have three related thioredoxin reductases

GO annotations related to this gene include G-protein coupled receptor activity and neuropeptide Y receptor activity

Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections

which results in the activation of several signaling cascades

Himmelfarb et al

SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Mammals have three related thioredoxinThis gene encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols