TTR mouse Monoclonal Antibody(3B5), 20ul Drug Development and Evaluation This gene encodes TBP

This gene encodes TBP

acting in cis to limit the elongation of individual chromosome ends

Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene

A similar protein in mouse has been reported to play a role in liver organogenesis

This locus encodes a member of the glycerate kinase type-2 family

TTR mouse Monoclonal Antibody(3B5), 20ul Drug Development and Evaluation This gene encodes TBPThis gene encodes transthyretin, one of the three prealbumins including alpha 1 antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported most mutations are related to amyloid