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GFAP Monoclonal Antibody, 100ul Dry Bath encoded by two separate genes

SKU: 48167094209

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GFAP Monoclonal Antibody, 100ul Dry Bath encoded by two separate genesThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

encoded by two separate genes

It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4

It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA

it functions as a regulator of a wide variety of downstream proteins

IGFL2 belongs to the insulin-like growth factor (IGF

GFAP Monoclonal Antibody, 100ul Dry Bath encoded by two separate genesThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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