Cyclophilin B Monoclonal Antibody(1B3), 100ul Pasteur Pipets Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been found for CDH18

and play a role in spindle formation during mitosis

blood coagulation

Mutations in this gene have been associated with Hodgkin lymphoma

Its expression can also be induced by tumor suppressor protein TP53

Cyclophilin B Monoclonal Antibody(1B3), 100ul Pasteur Pipets Alternatively spliced transcript variants encodingThe protein encoded by this gene is a cyclosporine binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T and B lymphocytes, and may regulate cyclosporine A mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.