DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging The product of this gene

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

Adaptor proteins are usually required for this activation

The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus

ACC-beta may be involved in the regulation of fatty acid oxidation

atherosclerosis and cancer

DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging The product of this geneThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome